ES2007339A6 - Procedimiento para preparar nueevos derivados de ergoleno halogenados. - Google Patents
Procedimiento para preparar nueevos derivados de ergoleno halogenados.Info
- Publication number
- ES2007339A6 ES2007339A6 ES8701211A ES8701211A ES2007339A6 ES 2007339 A6 ES2007339 A6 ES 2007339A6 ES 8701211 A ES8701211 A ES 8701211A ES 8701211 A ES8701211 A ES 8701211A ES 2007339 A6 ES2007339 A6 ES 2007339A6
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparing new
- new halogenated
- ergolene derivatives
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000561 anti-psychotic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical group [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU861719A HU196598B (en) | 1986-04-25 | 1986-04-25 | Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2007339A6 true ES2007339A6 (es) | 1989-06-16 |
Family
ID=10955843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8701211A Expired ES2007339A6 (es) | 1986-04-25 | 1987-04-24 | Procedimiento para preparar nueevos derivados de ergoleno halogenados. |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US4859682A (en]) |
| JP (1) | JPS62258379A (en]) |
| KR (1) | KR920008167B1 (en]) |
| CN (1) | CN87102944A (en]) |
| AT (1) | AT391472B (en]) |
| AU (1) | AU592637B2 (en]) |
| BE (1) | BE1001159A4 (en]) |
| CH (1) | CH669791A5 (en]) |
| CS (1) | CS268534B2 (en]) |
| DD (1) | DD256133A5 (en]) |
| DE (1) | DE3713768A1 (en]) |
| DK (1) | DK208887A (en]) |
| EG (1) | EG18272A (en]) |
| ES (1) | ES2007339A6 (en]) |
| FI (1) | FI871128A7 (en]) |
| FR (1) | FR2597869B1 (en]) |
| GB (1) | GB2189487B (en]) |
| GR (1) | GR870645B (en]) |
| HU (1) | HU196598B (en]) |
| IL (1) | IL82324A0 (en]) |
| IN (1) | IN165245B (en]) |
| IT (1) | IT1203976B (en]) |
| LU (1) | LU86853A1 (en]) |
| NL (1) | NL8700966A (en]) |
| NO (1) | NO165800C (en]) |
| PL (1) | PL152619B1 (en]) |
| PT (1) | PT84739B (en]) |
| SE (1) | SE466401B (en]) |
| SU (1) | SU1500161A3 (en]) |
| ZA (1) | ZA872931B (en]) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU196394B (en) * | 1986-06-27 | 1988-11-28 | Richter Gedeon Vegyeszet | Process for preparing 2-halogenated ergoline derivatives |
| KR20040104677A (ko) * | 2002-04-30 | 2004-12-10 | 비오갈 기오기스제르갸르 알티. | 신규의 온단세트론 결정 형태, 그 제조 방법, 그 신규의결정 형태를 함유하는 약학 조성물 및 이들을 이용한구역질 치료 방법 |
| US20240343692A1 (en) * | 2021-08-09 | 2024-10-17 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Selective psychedelic compounds |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE237837C (en]) * | ||||
| DE1936410A1 (de) * | 1969-07-17 | 1971-02-11 | Hoechst Ag | O-Acyl-lysergole und Verfahren zu ihrer Herstellung |
| AR206772A1 (es) * | 1972-07-21 | 1976-08-23 | Lilly Co Eli | Procedimiento para preparar una nueva d-2-halo-6-metil-8-ciano(carboxamido)metil ergolina |
| US3992385A (en) * | 1975-01-20 | 1976-11-16 | Eli Lilly And Company | 2,3-Dihydroergolines |
| CH619709A5 (en) * | 1975-03-14 | 1980-10-15 | Siphar Sa | Process for the preparation of carbamates of 2-halogenoergolines and 2-halogenoergolenes |
| DE2656344A1 (de) * | 1975-12-23 | 1977-07-07 | Sandoz Ag | Ergolinderivate, ihre verwendung und herstellung |
| US4035094A (en) * | 1976-03-11 | 1977-07-12 | Trw Inc. | Ball and socket joint |
| DK75177A (da) * | 1976-04-27 | 1977-10-28 | Sandoz Ag | Fremgangsmade til fremstilling af prostaglandiner |
| US4098790A (en) * | 1976-09-15 | 1978-07-04 | Eli Lilly And Company | Ergoline chlorination process |
| DE3001752A1 (de) * | 1980-01-16 | 1981-07-30 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen |
| DE3151912A1 (de) * | 1981-12-23 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
| DD237837A1 (de) * | 1983-11-29 | 1986-07-30 | 1086 Berlin,Otto-Nuscke-Str. 2/23,Dd | Verfahren zur herstellung von 2-bromergolinen |
| DE3403067A1 (de) * | 1984-01-30 | 1985-08-14 | Eckart Prof. Dr. 6500 Mainz Eich | Ergolin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
| DE3413657A1 (de) * | 1984-04-09 | 1985-10-17 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ergoline |
| HU193781B (en) * | 1985-06-21 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof |
| US4782152A (en) * | 1985-08-16 | 1988-11-01 | Eli Lilly And Company | Decyanation of pergolide intermediate |
| HU196394B (en) * | 1986-06-27 | 1988-11-28 | Richter Gedeon Vegyeszet | Process for preparing 2-halogenated ergoline derivatives |
-
1986
- 1986-04-25 HU HU861719A patent/HU196598B/hu not_active IP Right Cessation
-
1987
- 1987-03-13 FI FI871128A patent/FI871128A7/fi not_active Application Discontinuation
- 1987-04-21 US US07/040,938 patent/US4859682A/en not_active Expired - Fee Related
- 1987-04-22 PT PT84739A patent/PT84739B/pt not_active IP Right Cessation
- 1987-04-23 CN CN87102944A patent/CN87102944A/zh active Pending
- 1987-04-23 EG EG238/87A patent/EG18272A/xx active
- 1987-04-24 CH CH1577/87A patent/CH669791A5/de not_active IP Right Cessation
- 1987-04-24 DD DD87302104A patent/DD256133A5/de not_active IP Right Cessation
- 1987-04-24 PL PL1987265357A patent/PL152619B1/pl unknown
- 1987-04-24 CS CS872920A patent/CS268534B2/cs unknown
- 1987-04-24 LU LU86853A patent/LU86853A1/de unknown
- 1987-04-24 GR GR870645A patent/GR870645B/el unknown
- 1987-04-24 NL NL8700966A patent/NL8700966A/nl not_active Application Discontinuation
- 1987-04-24 ES ES8701211A patent/ES2007339A6/es not_active Expired
- 1987-04-24 SU SU874202410A patent/SU1500161A3/ru active
- 1987-04-24 NO NO871721A patent/NO165800C/no unknown
- 1987-04-24 IL IL82324A patent/IL82324A0/xx not_active IP Right Cessation
- 1987-04-24 BE BE8700445A patent/BE1001159A4/fr not_active IP Right Cessation
- 1987-04-24 IN IN326/CAL/87A patent/IN165245B/en unknown
- 1987-04-24 AU AU71945/87A patent/AU592637B2/en not_active Ceased
- 1987-04-24 FR FR878705838A patent/FR2597869B1/fr not_active Expired - Lifetime
- 1987-04-24 JP JP62100224A patent/JPS62258379A/ja active Granted
- 1987-04-24 AT AT0102287A patent/AT391472B/de active
- 1987-04-24 DK DK208887A patent/DK208887A/da not_active Application Discontinuation
- 1987-04-24 DE DE19873713768 patent/DE3713768A1/de not_active Withdrawn
- 1987-04-24 IT IT20271/87A patent/IT1203976B/it active
- 1987-04-24 ZA ZA872931A patent/ZA872931B/xx unknown
- 1987-04-24 SE SE8701700A patent/SE466401B/sv not_active IP Right Cessation
- 1987-04-24 KR KR1019870003970A patent/KR920008167B1/ko not_active Expired
- 1987-04-27 GB GB8709893A patent/GB2189487B/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980504 |